I got a couple of things professionally framed recently - signed prints by Peter Blake and Eduardo Paolozzi (my aunt knew him - he was Stuart Sutcliffe's tutor in Hamburg). Anyway, the framer put them under special glass (don't know precisely what, sorry), and also mounted them on non-acidic paper. If you speak to a decent framer they'll know what to do, and don't try to do it cheaply if it's a valuable item.
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